Abstract: Guided wave interference in marine data has the characteristics of high energy, wide frequency, and dispersion, just like surface wave interference. Guided wave interference seriously affects the signal-to-noise ratio of data. If it cannot be efficiently removed, it will cause great difficulties for subsequent data processing and interpretation. This article summarizes a process for guided wave suppression. Firstly, by utilizing the characteristics of guided wave dispersion, a high-precision dispersion spectrum is generated, and the picked dispersion curve is used to forward model the guided wave. Then, the guided wave model is subtracted from the original data through adaptive subtraction to achieve the purpose of suppressing guided wave interference. This process can perfectly suppress guided wave interference and maximize the protection of effective signals, making it highly practical.