Abstract: In seismic-geological data integration, the time-depth relationship resulting from well-seismic calibration serves as a bridge to operate conversions among depth-domain logging data, geological data, and time-domain seismic data.By obtaining better insight into well-seismic calibration results, the reliability and accuracy of the time-depth relationship after seismic calibration can be improved, thereby enhancing the precision of structural interpretation, variable velocity mapping, and, more broadly, reservoir research.In this paper, a comprehensive time-depth relationship analysis method was proposed to improve the accuracy of well-seismic calibration.The following procedures were carried out, namely: velocity analysis according to the sedimentary facies belts, analysis of the seismic profile of the combined wells, and velocity relationship analysis of the VSP from the perspective of analyzing the main factors that affect the results of the seismic calibration.An application of a seismic-geological integration to improve the accuracy of the time-depth relationship was carried out.Taking sedimentary strata from several depressions, their single-well calibrations, seismic horizon tracking of individual geological interfaces, and applications of VSP velocity data were extended to the calibration of different sedimentary facies belts based on data from multiple wells, and were used in the quality control of the tracking of multiple seismic horizons, as well as for rapid stratigraphic correlation.The results showed that the proposed method can be applied to the inspection of the calibration results of the time-depth relationship in clastic sedimentary strata.By this method, the accuracy and precision of the time-depth relationship after well-seismic calibration can be improved.The proposed method has broad application prospects for structural analysis and reservoir evaluation.